Even the element hydrogen was named because it was originally generated (genos in Greek means ‘descent’) from water. You probably recognise hydro- as being related to ‘water’ (it is from the Greek word for water), since it occurs in words like hydroelectric, hydrothermal, hydroponics, hydrostatic, etc. Coming up very soon are the words ‘hydrophobic’ and ‘hydrophilic’. The scales were extrapolated to residues which are more hydrophilic than glycine.During your studies you will meet a number of words which have Latin or Greek roots and whose meaning you may be able to work out. The values in the table below are normalized so that the most hydrophobic residue is given a value of 100 relative to glycine, which is considered neutral (0 value). In a protein, hydrophobic amino acids are likely to be found in the interior, whereas hydrophilic amino acids are likely to be in contact with the aqueous environment. The hydrophobicity index is a measure of the relative hydrophobicity, or how soluble an amino acid is in water. Hydrophobicity Index for Common Amino Acids Peptide Hydrophobicity/Hydrophilicity Analysis: Sequence:ġ-Pyrenemethylamine HCL Abz Abz/DNP Abz/Tyr (3-NO2) Amide Cyclic BOC DABCYL DABCYL/Glu(EDANS)-NH2 Double Disulfide bridge EDANS/DABCYL Glu(EDANS)-NH2 MCA/DNP mini-PEG1 mini-PEG2 Mono Disulfide bridge P-Nitroanilide Succinylation Triple Disulfide bridge Tyr (3-NO2)Īmino Acids with Hydrophobic Side Chain - AliphaticĪmino Acids with Hydrophobic Side Chain - AromaticĪmino Acids with Polar Neutral Side ChainsĪmino Acids with Electricaly Charged Side Chains - AcidicĪmino Acids with Electricaly Charged Side Chains - Basic Peptide Synthesis Application and Recommended Purity.Peptide Synthesis Frequently Asked Questions.Reverse Translation of Amino Acid Sequences.Amino Acid Converter: Three-letter to One-letter and One-letter to Three-letter.Peptide Synthesis Hydrophobicity Hydrophilicity Analysis.Peptide Synthesis for Peptide Array/Library.
Peptide Hydrophobicity/Hydrophilicity Analysis Tool
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